TABLE 1.Physiological properties of layer 2/3 pyramidal neurons and interneurons
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PN (13) | FS (9) | RSNP (14) | IS (17) | |
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Resting potential, mV | –68.8 ± 1.1 | –61.9 ± 0.8 | –59.0 ± 2.0 | –55.0 ± 1.5 |
Input resistance, MΩ | 272 ± 18 | 230 ± 28 | 348 ± 35 | 349 ± 39 |
Spike amplitude, mV | 90.5 ± 1.2 | 79.4 ± 1.7 | 85.5 ± 1.9 | 70.7 ± 9.8 |
Spike duration, ms | 1.4 ± 0.06 | 0.6 ± 0.04 | 0.9 ± 0.06 | 0.8 ± 0.04 |
AHP, mV | –3.7 ± 0.6 | –19.2 ± 1.3 | –10.2 ± 0.9 | –12 ± 0.8 |
Freq. accommodation, % | 68 ± 2.7 | 11 ± 2.4 | 55 ± 5.8 | ND |
Sag potential, mV | 3.0 ± 0.4 | 3.8 ± 0.3 | 11.5 ± 1.2 | 10.7 ± 2.1 |
Values are given as mean ± SE. PN, pyramidal neuron; FS, fast spiking; RSNP, regular spiking non-pyramidal; IS, irregular
spiking; AHP, afterhyperpolarization; ND, not determined (due to the irregular nature of spiking in IS cells). Physiological
parameters were measured as described in METHODS. Numbers of neurons are in parentheses.